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Lappaconitine hydrobromide

[Product name]: lappaconitine hydrobromide

[English name]: Lappaconite Hydrobromide

[Product specification]: lappaconitine hydrobromide: 98%

[Appearance]: This product is white crystal, odorless and bitter in taste.

[Extraction source]: an alkaloid (Rabaconitine) extracted from the root of Aconitum altissima, a Ranunculaceae plant

[Detection method]: HPLC ≥ 98%


Sample application

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Detailed introduction

[Product Overview]

The alkaloid isolated from Aconitum nitidum is a non narcotic analgesic, which has a strong analgesic effect, equivalent to that of morphine, 7 times that of the ordinary analgesic drug aminopyrine. The analgesic effect is equivalent to that of dolantin, which lasts longer, and is a substitute for tramadol. In addition, it has antipyretic, local anesthesia and detumescence effects without dependence.

[Other Name]: Aconitine; Lappaconitine hydrobromide; Rabaconitine; Rabaconitine hydrobromide; Rito

[Pharmacological properties]: melting point 267~272 ℃, slightly soluble in methanol, ethanol, water, soluble in hot dilute methanol, hot dilute ethanol, insoluble in non-polar solvent.

[Molecular Formula]: C32H44N2O8.HBr.H2O

[Molecular weight]: 84.7000

[CAS No.]: 32854-75-4

[Precise mass]: 584.31000

[PSA]︰126.79000

[LogP]︰2.23250

[Density]: 1.35 g/cm3

[Melting point]: 217-218oC

[Boiling point]: 720.7oC at 760 mmHg

[Flash point]: 389.7oC

[Refractive index]: 1.623

[Water solubility]: insoluble

[Package specification]: standard package: 25kg/cardboard bucket; Bulk cargo: 1kg/bag

[Storage conditions]: Keep in a cool, dry and ventilated place, and avoid direct sunlight.

[Shelf life]: 24 months

[Product Application]: Drugs


[Heavy metal detection]

Total

≤10ppm

Accord with

Arsenic

≤10ppm

Accord with

Lead

≤10ppm

Accord with

[Microbiological Testing]

Total number of colonies

≤1000cfu/g

Accord with

Yeast & Mold

≤100cfu/g

Accord with

Yeast & Mold

Negative

Accord with

Salmonella

Negative

Accord with

Staphylococcus

Negative

Accord with


[Efficacy of lappaconitine hydrobromide]

Lappaconitine hydrobromide: it is anti-inflammatory and antipyretic, and has obvious inhibitory effect on the increase of capillary permeability, exudation, swelling, etc. caused by various inflammatory models, and can enhance the function of adrenal cortex. At the same time, it can inhibit the permeability of capillaries, eliminate the swelling of auricles, toes, joints and lower limbs, and inhibit the formation of intrabulbar buds. It has many health characteristics, such as.

1. Cancer pain, headache, toothache, shoulder and arm pain, cervical pain, low back pain, calculus pain, traumatic pain, rheumatic pain, gastrointestinal ulcer pain, neuralgia, sciatica, various kinds of pain caused by inflammation of women, and postoperative pain.

2. Used for fever caused by cold, fever and other reasons.

3. It is used to diminish inflammation, swelling, pain and promote wound healing after operation.

4. It can replace dolantin and assist in detoxification (injecting dolantin and morphine addicts).

5. Enhance immunity, stimulate the proliferation of reticuloendothelial cells, enhance the phagocytosis of white blood cells and mononuclear macrophages, and thus improve immunity.


[Application of lappaconitine hydrobromide]                                                

It can be used as medicine or injection. The effect of lappaconitine hydrobromide is powerful analgesia, and the analgesic effect is as much as seven times that of ordinary analgesics. The analgesic effect of lappaconitine is very long, safe, cooling and antipyretic. It has a good antipyretic effect on many kinds of fever symptoms, and can play a cooling role well. It has a significant inhibitory effect on the increase of capillary permeability and exudation caused by a variety of inflammation.

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