[Product Overview]

"Betulin, also known as betulin, betulin and birch brain, is soluble in ethanol, ether, chloroform and benzene, and slightly soluble in cold water, petroleum ether and other organic solvents. The plant source is the extraction of birch bark. Betulin has anti-inflammatory, anti-virus, inhibition of protein dissolution in hair fibers, improvement of damaged hair luster, and promotion of hair growth and other activities, and can be used in food, cosmetics, medicine and other industries.

[Alias]: Xiangshusu; Betulin; Birch brain; BETA aromatic resin alcohol; beta incense tree essence; Betulin alcohol; Β- Vanillin

[CAS No.]: 473-98-3

[Molecular Formula]: C30H50O2

[Molecular weight]: 442.72

[Test index]

1. Loss on drying: ≤ 6.0% (test method in Chinese Pharmacopoeia)

2. Ash content: ≤ 9% (Chinese Pharmacopoeia test method)

3. Heavy metal: ≤ 10ppm (detection method in Chinese Pharmacopoeia)

4. Pesticide residues: ≤ 2ppm

5. Solvent residue: ≤ 0.5%

6. Total number of bacteria:<1000CFU/g Yeast Monella

7. Mold and yeast:<100CFU/g Salmonella

8. Salmonella: Negative without Ecoli

9. Escherichia coli: Negative None

[Detection method]: HPLC ≥ 98%

Conditional stationary phase: C18 (150 × 2)mm 5 μ

Mobile phase: acetonitrile/water=30:70

Injection volume: 10 μ l

Column temperature: 30 ℃

Flow rate: 0.2ml/min

Detection wavelength: 270nm

[Physical and chemical properties]: It belongs to pentacyclic triterpene compounds. Crystallization, melting point 248~251 ℃ (methanol chloroform). White crystal (benzene ethyl acetate). The melting point is 238 ℃. Optical rotation[ α] D15+20 ° (c=2, pyridine). 240 ℃ (1.33Pa) sublimation. The solvate containing 1mol ethanol is needle shaped crystal, which sublimates at 170~180 ℃ (10.67Pa) after drying.

[Melting point]: 256-257 ℃

[Solubility]: soluble in ethanol, chloroform and benzene, slightly soluble in cold water, petroleum ether, etc.

[Package specification]: standard package: 25kg/cardboard bucket; Bulk cargo: 1kg/bag

[Production process]: screening raw materials, cleaning raw materials, three times of extraction, purification, spray drying into powder, screening sterilization, packaging.

[Storage conditions]: The product should be sealed and shaded, and stored in a dry, cool and well ventilated place.

[Shelf life]: 24 months

[Application field]: food, cosmetics, medicine and other industries

[Efficacy of betulin]

Betulin has a wide range of biological activities. It is verified by a variety of animal models and cell models that betulin has such functional characteristics as expectorant and cough relieving, melanin inhibiting, blood lipid lowering, liver protection and anti-cancer, anti-inflammatory, anti-virus, anti-tumor, anti HIV, and improvement of Alzheimer's disease (AD).

1. Inhibiting melanin formation

2. Hypolipidemic

3. Hepatoprotective effect

4. Anti cancer and anti-tumor effects

5. Anti inflammatory and antioxidant activity

6. Anti HIV

7. Protect hippocampal neurons

[Application of betulin]

Betulin has anti-inflammatory, anti-virus, inhibiting protein dissolution in hair fiber, improving damaged hair luster, promoting hair growth and other activities, and can be used in food, cosmetics, medicine and other industries.

1. Medicine: Betulin is mainly used as a medical intermediate. Betulin and its derivatives show great potential in HIV and cancer treatment as biological agents. At the same time, it is used to relieve cough and expectoration, treat allergic rhinitis, insomnia, depression, etc.

2. Food: It has been studied as a preservative for meat products.

3. Cosmetics: Betulin can inhibit the activity of collagenase and the proliferation of skin cells. It has a strong anti-aging effect, and can be used to regulate skin, smooth skin and prevent chaps. It is also a good external penetration aid.

4. Daily chemical industry: In hair products, birch brain can reduce the protein dissolution in hair fibers, improve the luster of damaged hair, and promote hair growth.